Disease Modeling
The current situation
Disease modeling can be a powerful tool to help researchers understand physiological phenomena and the onset, progression, and treatment of diseases. These insights, in turn, can be used by government organizations to plan research, develop guidelines, and make policy recommendations to improve quality of care. Specifically, modeling can work hand-in-hand with clinical research and clinical judgment to:
- Integrate current information
- Generate hypotheses
- Test assumptions
- Design research
Once built, a model can be used to explore a variety of clinical questions that cannot be addressed by empirical methods.
The Archimedes advantage
The Archimedes Model is a carefully validated mathematical model built at a level of physiological detail that corresponds to the functions of organs. It retains the continuous nature, interactions, and progression of biological variables, and therefore can more accurately describe the complexity of diseases.
Archimedes spans multiple conditions in a single integrated model. Because it is programmed using object oriented methods, it can be easily expanded to incorporate deeper levels of physiology, new physiological pathways, and new diseases. Additional physiological pathways and new diseases are easily integrated with existing parts of the Model. In this way the Model can be used to explore questions that span conditions and interventions, such as the effects of changes in physiology on clinical outcomes and utilization of resources.
How you can use the Archimedes Model
Modeling & Consulting Services. Archimedes has a world-class team of scientists and physicians who will work with you to run custom simulations and build custom disease models to meet your needs. They have decades of experience creating, testing, and refining disease models. You can be confident that new disease models we help you develop will mimic the physiological, clinical, or administrative processes they are built to represent as closely as possible.
