Clinical Trial Simulation
The current situation
Each year, government organizations initiate hundreds of major clinical trials. These trials can cost millions or even hundreds of millions of dollars. However, many fail to produce actionable information because the sample size was too small or the trial duration too short. Other trials are unnecessarily expensive or not feasible to conduct.
By simulating clinical trials before they are executed, the Archimedes Model can help government agencies reduce uncertainty, avoid costly errors, and mitigate risk. Archimedes Model users can:
Preview the outcomes of specific interventions within realistic, simulated healthcare systems
Identify the study populations, sample sizes, study protocols and duration, and outcome definitions required to achieve a statistically significant effect
- Model the impact of population-level screening programs
The Archimedes advantage
The Archimedes Model is a comprehensive simulation model built to represent physiologic, clinical, and administrative healthcare events as they occur in reality.
The Model has been in use since 1993, and has been constantly refined and validated with information and results from hundreds of national and international datasets, clinical trials, and studies.
How you can use the Archimedes Model
ARCHeS. ARCHeS is a web-based analytics and visualization tool that can run unlimited treatment and outcomes simulations for the following conditions: chronic obstructive pulmonary disease, congestive heart failure, coronary artery disease, diabetes and its complications, dyslipidemia, hypertension, metabolic syndrome, obesity, smoking, and stroke.
ARCHeS gives users the power to specify population baseline characteristics, subpopulations of interest, inclusion and exclusion criteria, and to assess the impact of specific interventions (for example, the use of antihypertensive or antidiabetic agents or the impact of obesity management and/or smoking cessation).
ARCHeS can also be used to model the impact of new or hypothetical treatments, either by drawing from results of Phase 2 clinical trials or by specifying treatment effects on biomarkers and/or health outcomes. More...
Modeling & Consulting Services. Archimedes provides comprehensive support to help users run custom clinical trial simulations. For questions beyond the scope of ARCHeS, our team of scientists and physicians can help you to develop objectives, design and run simulations, and analyze and interpret the data. More...
Webinar and Case Studies
See how the Model is used for trial simulation: register for immediate access to our archived webinar and case studies.