Archimedes is now part of Evidera!

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How ARCHeS Works
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Integrating Real-World and Simulation Data

Until recently ARCHeS was mainly been used to run virtual population simulations and get answers to questions that cannot be answered by traditional clinical trials or cohort studies due to cost, time or ethical constraints.

The recent addition of ARCHeS Population Explorer (ARCHeS PE) enables users to integrate and analyze their own real-world data with simulation data and uncover evidence useful to designing trials and understanding outcomes.

This single environment for the analysis of disparate datasets can handle claims, EMR, clinical trial, and modeled data, enabling the calculation and translation of value across multiple settings.

ARCHeS Trial Designer

ARCHeS TD enables users to set up their own virtual clinical trial or cohort study. Using a web interface users can:

  • define populations and subpopulations
  • specify background care
  • specify eligibility criteria
  • apply standard or custom interventions
  • set up a multi-arm study
  • design custom care processes


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The Archimedes Model

When a simulation setup is complete, the study is submitted to the Archimedes Model (the “Simulator”). The Simulator simulates each virtual person in the population through disease models and protocols that deliver both standard care and the interventions of interest.

Download the Model technical reports

ARCHeS Outcomes Analyzer

The forecast datasets generated by the Archimedes Model are reported back to users through ARCHeS OA.

This component enables users to create and export a large number of tables and figures to examine different combinations of interventions, outcomes, populations, and time horizons. Users can also explore the effects of changing assumptions about costs, performance levels, and other variables.

ARCHeS Population Explorer (New)

ARCHeS PE is an analysis and reporting tool that enables users to understand the effects of changes in population composition on outcomes using their own real-world data or Archimedes simulation data. 

Once the data is loaded, users can create populations from different sources, interactively vary inclusion/exclusion criteria and the distribution of baseline characteristics, and observe the effects on outcomes in real time. Try ARCHeS PE (for free for registered users).