Clinical Trial Simulation
The current situation
Conducting successful clinical trials is a key component of product development for pharmaceutical, biotechnology, diagnostic, and medical device companies.
However, clinical trials require substantial time and resource investments, and pressure to deliver results rapidly and within budget has never been higher. Because of this, it is critical to design trials that yield conclusive and meaningful results, and whose probability of success has been maximized.
The Archimedes advantage
The Archimedes Model is a comprehensive, validated simulation model of human physiology, diseases, clinical care interventions, patient and physician behaviors, and healthcare systems.
The Model has been continuously updated and validated since 1993, and 9 of the 10 top pharmaceutical organizations worldwide have used it to demonstrate the value of their products. By using the Model to simulate clinical trials before they are implemented, companies can:
- Improve sample size estimation by better understanding how and when events are likely to occur
- Sharpen size and composition estimates for eligible population(s)
- Optimize trial design to maximize your probability of success with regulatory agencies
Preview potential trial outcomes across simulated healthcare systems
How you can use the Archimedes Model
ARCHeS – ARCHeS is a comprehensive web-based tool that provides direct access to the Archimedes Model, enabling users to set up and run clinical trial simulations from their desktop.
With ARCHeS, researchers can examine treatments and outcomes related to the following conditions: chronic obstructive pulmonary disease, congestive heart failure, coronary artery disease, diabetes and its complications, dyslipidemia, hypertension, metabolic syndrome, obesity, smoking, and stroke.
ARCHeS can also be used to explore the impact of new or hypothetical treatments, for example by drawing on Phase 2 research results, specifying biomarker effects, and/or focusing on specific health outcomes.
Modeling and Consulting Services – ARCHeS is currently limited to simulations related to diabetes, cardiovascular disease, and the other conditions listed above. However, the Archimedes Model spans a wider range of diseases, including multiple cancers and asthma.
For clinical trial simulations that cannot be addressed with ARCHeS, or for novel diseases not yet in the Model, Archimedes has dedicated support teams available to help you design and run custom clinical trial simulations.
Webinar and Case Studies
See how the Archimedes Model is used to simulate clinical trials: register now for immediate access to our archived webinar and case studies.